The chapters are organised around axes of humanism, historiography and cultural production, and cover many areas including literature, science, music, religion, education, technology, artistic production and economics. The diffusion of the Renaissance throughout Italian territories is emphasised.

This first substantial history of Italian literature to appear in the English language for forty years provides a comprehensive survey of Italian writing from its earliest origins up to the present day. Leading scholars describe and assess the work of writers who have contributed to the Italian literary tradition, including Dante, Petrarch and Boccaccio, the Renaissance humanists, Machiavelli, Ariosto and Tasso, pioneers and practitioners of commedia dell'arte and opera, and the contemporary novelists Calvino and Eco.

Embracing the whole of Italian literature, from the early thirteenth century to the present, The Oxford Companion to Italian Literature takes a broad view of what constitutes literature, covering historical writing, travel writing, theatre, and philosophy as well as the novel, poetry, literary dialogues, and critical theory.